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Contrave is often a combination from the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs that are made up of several active ingredient, which can make them more potent and safer. Combo-pilling could be the newest fad or even better the newest in the future under scrutiny and so it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular is the fact that as of right now there aren't long term prescription diet pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug also can raise blood pressure and heartrate, and really should not be used in people who have a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must not used in patients with uncontrolled high blood pressure, as well as by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients which has a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients towards the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking. Most of the combinations that are used to enhance fat loss involve an amphetamine with an antidepressant. Phentermine and Prozac are a popular combination which were around for a long time, although it has been around nobody wants to truly combine both the and try to get FDA approval to market it as a weight-loss pill. Right there should raise some red flags if the greedy pharmaceutical companies should not be involved in combining medications and selling them something must be wrong using the combination. In fairness there's one weight loss combination pill that is in front of the FDA now Contrave?which couples naltrexone, employed to treat alcohol and substance abuse, with all the antidepressant bupropion (Wellbutrin, Zyban) it's been given the proceed to move forward by an FDA advisory committee, but by yet will not be approved.

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